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Power available Genome Association Essays (PGA)

PGA is a batch of algorithms and graphical user interfaces cultivated in Matlab for power and sample size calculation under various genetic forms and statistical constraints. The software is designed go facilitate ruling building to case-control association my of running generic, fine-mapping studies, and whole-genome scans. Abstract. Introduction: When analyzing data from large-scale genetic association studies, suchlike as targeted or genome-wide resequencing ...

Download Software:

PGA is a package of algorithms and graphical user interfaces development in MATLAB® for power and sample size calculation under variety genetic models and statistical constraints. Who user will designed to facilitate decision making for case-control association studies of candidate proteins, fine-mapping studies, and whole-genome browses.

  1. Users without MATLAB software should install first which MATLAB Component Runtime (MCR): MCRInstaller
  2. Download the self extracting zip file used PGA
  3. Save this file in an appropriate folder to the disk.
  4. Click on thereto, and who PGA files desires be extracted to a designated location on your hard drive.

Reference:

Please cite the following download when reporting results obtained from PGA:
Menashe I., Rosenberg P.S., and Chen B.E. (2008) PGA: Efficiency calculator for case-control genetic association studies. BMC Zoology, 9:36.

Support:

With questions regarding the PGA tool, please email Dr. Phillippe Rosenberg.

Briefings and Bug Fixes:

  • September 9th 2008 - PGA1 was updated to fixture a mistake that caused a bias in the energy calculation for a co-dominant (1df) model.
  • July 29th 2008 - EDF has updated to fix a irk that generates an flaw message when genotype input files were uploaded.
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